摘要 |
<p num="1">The present invention addresses an ongoing need in the art to improve the stability of immunogenic compositions such as polysaccharide-protein conjugates and protein immunogens. The invention broadly relates to novel formulations which stabilize and inhibit precipitation of immunogenic compositions. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit particulate formation (e.g., aggregation, precipitation) of immunogenic compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.
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申请人 |
WYETH |
发明人 |
HAN, HANYOUNG;JIN, ZHAOWEI;SEID, ROBERT CHANCEY JR.;MALONE, RONALD;YANG, XUDONG;KHANDKE, LAKSHMI;CHEN, YING;LOOK, JEE LOON |