发明名称 |
Methods for preventing strokes by inducing tolerance to E-selectin |
摘要 |
The present invention provides a method for reducing stroke-related tissue damage by treating a mammal with E-selectin. Preferably, this treatment induces E-selectin tolerance in the mammal. Another aspect of the invention is a method for inducing E-selectin tolerance in a mammal through intranasal administration of E-selectin, preferably including booster administrations. The present methods are especially adapted for use in patients at increased risk of stroke or who may become at increased risk of stroke.
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申请公布号 |
US2007253975(A1) |
申请公布日期 |
2007.11.01 |
申请号 |
US20070820326 |
申请日期 |
2007.06.19 |
申请人 |
HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH |
发明人 |
HALLENBECK JOHN M.;TAKEDA HIDETAKA;SPATZ MARIA |
分类号 |
A61K38/00;A61K39/39;A61K9/00;A61K38/11;A61K38/12;A61K38/17;A61K39/00;A61P1/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P9/14;A61P37/06 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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