| 摘要 |
The present invention relates to compounds of formulae (III) and (IV) <IMG> wherein R2 is H or CH3, and R3 is <IMG> wherein R6 is trifluoromethyl, phenyl optionally substituted with one or more halogens or branched (C4-7) alkyl groups, or branched (C4-7) alkyl; either of R7 or R8 is trifluoromethyl, halogen, phenyl optionally substituted with one or more halogens or branched (C4-7) alkyl groups, or branched (C4-7) alkyl, while the other is hydrogen or halogen; and X is hydrogen or halogen, or a solvate thereof and their use in the treatment of androgen responsive and mediated diseases.
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