| 发明名称 |
PROCESS FOR THE PREPARATION OF A GLUCOKINASE ACTIVATOR |
| 摘要 |
Provided is a process for the preparation of 2(R)-(3-chloro-4-methanesulfonyl- phenyl)-3-((R)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide and its isopropanol solvate as a glucokinase activator which increases insulin secretion in the treatment of, for example, type II diabetes. |
| 申请公布号 |
WO2007115968(A2) |
申请公布日期 |
2007.10.18 |
| 申请号 |
WO2007EP53153 |
申请日期 |
2007.04.02 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;DANIEWSKI, ANDRZEJ ROBERT;LIU, WEN;RADINOV, ROUMEN NIKOLAEV |
发明人 |
DANIEWSKI, ANDRZEJ ROBERT;LIU, WEN;RADINOV, ROUMEN NIKOLAEV |
| 分类号 |
C07D319/06;C07C315/04;C07D241/20 |
主分类号 |
C07D319/06 |
| 代理机构 |
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