发明名称 |
Genetically Engineered Pyrroloquinoline Quinone Dependent Glucose Dehydrogenase Comprising an Amino Acid Insertion |
摘要 |
The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH) comprising an amino acid insertion between positions 428 and 429 as corresponding to the amino acid sequence known from Acinetobacter calcoaceticus, to genes encoding such variant s-GDH, to proteins of such s-GDH variants with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugars, especially of glucose in a sample.
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申请公布号 |
US2007243566(A1) |
申请公布日期 |
2007.10.18 |
申请号 |
US20050632672 |
申请日期 |
2005.07.19 |
申请人 |
BOENITZ-DULAT MARA;LAGGERBAUER JESSICA;SCHMUCK RAINER;KRATZSCH PETER;KNAPPE WOLFGANG-REINHOLD |
发明人 |
BOENITZ-DULAT MARA;LAGGERBAUER JESSICA;SCHMUCK RAINER;KRATZSCH PETER;KNAPPE WOLFGANG-REINHOLD |
分类号 |
C12N9/00;C07H21/04;C12M1/00;C12N5/06;C12N15/00;C12P1/04;C12Q1/54 |
主分类号 |
C12N9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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