发明名称 beta-L-2'-DEOXY-NUCLEOSIDE FOR TREATMENT OF HEPATITIS B
摘要 <P>PROBLEM TO BE SOLVED: To provide a new treating agent of infection with hepatitis B virus. <P>SOLUTION: The pharmaceutical composition contains &beta;-L-2'-deoxycytidine exemplified by the compound of the formula [wherein, R is selected from the group consisting of H, a straight chained, a branched or cyclic alkyl, a CO-alkyl, a CO-aryl, a CO-alkoxyalkyl, a CO-aryloxyalkyl, a CO-substituted aryl, an alkylsulfonyl, an arylsulfonyl, an aralkylsulfonyl, an amino acid residue, mono, di, or triphosphate, or a phosphate derivative; and BASE is a purine or pyrimidine base which may be optionally substituted]. <P>COPYRIGHT: (C)2008,JPO&INPIT
申请公布号 JP2007269798(A) 申请公布日期 2007.10.18
申请号 JP20070122896 申请日期 2007.05.07
申请人 INDENIX PHARMACEUTICALS LTD;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;GOSSELIN GILLES;IMBACH JEAN LOUIS;BRYANT MARTIN L 发明人 GOSSELIN GILLES;IMBACH JEAN LOUIS;BRYANT MARTIN L
分类号 A61K31/7068;C07H19/073;A61K9/20;A61K9/48;A61K31/513;A61K31/522;A61K31/662;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7072;A61K31/7076;A61K31/708;A61P1/16;A61P31/12;A61P31/20;C07H19/06;C07H19/10;C07H19/16;C07H19/173;C07H19/20 主分类号 A61K31/7068
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