摘要 |
<p>The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein R<sub>a</sub>, R<sub>b</sub>, and R<sub>2</sub> are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.</p> |
申请人 |
SYNTA PHARMACEUTICALS CORP |
发明人 |
SUN, LIJUN;KOYA, KEIZO;CHEN, SHOUJUN;JIANG, JUN;YING, WEIWEN;FOLEY, KEVIN;BORELLA, CHRISTOPHER;LI, HAO;INOUE, TAKAYO;DU, ZHENIJIAN;WU, YAMING;ZHANG, MEI |