发明名称 ISOXAZOLE COMBRETASTIN DERIVATIVES FOR THE TREATMENT OF DISORDERS.
摘要 <p>The invention relates to compounds of structural formula (I); or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein R<sub>a</sub>, R<sub>b</sub>, and R<sub>2</sub> are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.</p>
申请公布号 MX2007009888(A) 申请公布日期 2007.10.16
申请号 MX20070009888 申请日期 2006.02.16
申请人 SYNTA PHARMACEUTICALS CORP 发明人 SUN, LIJUN;KOYA, KEIZO;CHEN, SHOUJUN;JIANG, JUN;YING, WEIWEN;FOLEY, KEVIN;BORELLA, CHRISTOPHER;LI, HAO;INOUE, TAKAYO;DU, ZHENIJIAN;WU, YAMING;ZHANG, MEI
分类号 C07D261/08;A61K31/42;A61P35/00;C07D413/04 主分类号 C07D261/08
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