发明名称 |
PYRIDYL NON-AROMATIC NITROGENATED HETEROCYCLIC-1-CARBOXYLATE ESTER DERIVATIVE. |
摘要 |
<p>[PROBLEMS] To provide a compound which can be used for the treatment of a disease associated with a fatty acid amide hydrolase (FAAH), particularly pollakiuria/incontinence of urine, overactive bladder and/or pain. [MEANS FOR SOLVING PROBLEMS] It is found that a novel pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative and a pharmaceutically acceptable salt thereof have a potent FAAH inhibitory activity. The derivative is superior in increasing the effective bladder capacity and in improving pollakiuria and has an anti-allodynic effect. Therefore, this compound can be used for the treatment of pollakiuria/incontinence of urine, overactive bladder and/or pain.</p> |
申请公布号 |
MX2007010076(A) |
申请公布日期 |
2007.10.16 |
申请号 |
MX20070010076 |
申请日期 |
2006.02.16 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
CHIKASHI SAITOH;TAKATOSHI KANAYAMA;KENTARO SATO;TAKAHIRO ISHII;TAKASHI SUGANE;JUN MAEDA;FUMIE NARAZAKI;AKIO KAFEFUDA;TATSUHISA TAKAHASHI;JOTARO SUZUKI;CHISATO KANAI |
分类号 |
C07D213/65;A61K31/4545;A61K31/4709;A61K31/4725;A61K31/496;A61K31/5377;A61K31/55;A61P13/00;A61P25/00;A61P43/00;C07D213/80;C07D213/82;C07D401/12;C07D401/14;C07D405/14;C07D413/12;C07D413/14;C07D417/14 |
主分类号 |
C07D213/65 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|