MUCIN-TYPE GLYCOPEPTIDE HAVING POLYLACTOSAMINE BACKBONE

摘要

The object is to provide: a novel compound which is useful as a primer for use in the production of a mucin-type glycopeptide having a polylactosamine backbone which is useful in a wide variety of applications including a material for a biochemical study, a pharmaceutical and a food and has a difficulty in production before this time; and a method for production of a glycopeptide using the primer. Disclosed are: a mucin-type glycopeptide derivative which has a novel polylactosamine backbone having an aldehyde group or a ketone group at the terminus and also having an amino acid residue which is cleavable with a protease (i.e., a compound represented by the formula (I)); a simple production method for a mucin-type glycopeptide having a polylactosamine backbone by using the derivative as a primer; and a method for production of a mucin-type peptide having a polylactosamine backbone by synthesizing a glycopeptide having a specific peptide sequence using a mucin-type glycoamino acid having a polylactosamine backbone which has been synthesized previously.