COMBINATION IMMEDIATE RELEASE CONTROLLED RELEASE LEVODOPA AND CARBIDOPA DOSAGE FORMS

摘要

The present invention relates to pharmaceutical dosage forms of a combination of carbidopa and levodopa comprising both immediate release and controlled release components for the treatment of ailments associated with depleted amounts of dopamine in a patient's brain tissue, which dosage forms display no food effect or at least substantially avoid the food effect, and a related method of treatment for a patient in which the bioavailability of levodopa under non-fasting conditions is equivalent to the bioavailability under fasting conditions.