发明名称 |
METHODS FOR PRODUCING SOLUBLE MULTI-MEMBRANE-SPANNING PROTEINS |
摘要 |
Methods for producing membrane-spanning polypeptides in high yields, with native conformation, and/or in soluble form include solubilizing in non-ionic or zwitterionic detergents as well as use of promoters and expression vectors for expressing high yields of membrane-spanning polypeptides in bacterial cells. Mutated promoters provide tight control of membrane-spanning polypeptides in bacterial cell hosts. |
申请公布号 |
KR20070100307(A) |
申请公布日期 |
2007.10.10 |
申请号 |
KR20077016684 |
申请日期 |
2007.07.20 |
申请人 |
GENENTECH, INC. |
发明人 |
ERNST JAMES A.;YANSURA DANIEL G.;KIM, HOK SEON |
分类号 |
C07K14/705;C07K16/18;G01N33/53 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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