| 摘要 |
A time release composition is provided containing: a chromium complex having formula 3 <?in-line-formulae description="In-line Formulae" end="lead"?>[Cr<SUB>3</SUB>O(carboxylate)<SUB>6</SUB>(ligand)<SUB>3</SUB>]<SUP>+</SUP> (3)<?in-line-formulae description="In-line Formulae" end="tail"?> wherein carboxylate is a C2-C5 alkyl carboxylate and wherein 'ligand' is a ligand that (i) renders the chromium complex insoluble or only slightly soluble in water and (ii) is acid labile, being readily displaced under acidic conditions below pH=4 and replaced by water to make the resulting water soluble complex 2 <?in-line-formulae description="In-line Formulae" end="lead"?>[Cr<SUB>3</SUB>O(carboxylate)<SUB>6</SUB>(H<SUB>2</SUB>O)<SUB>3</SUB>]<SUP>+</SUP> (2),<?in-line-formulae description="In-line Formulae" end="tail"?> and the use of the time release composition for the time release delivery of complex 2.
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