| 发明名称 |
Novel compounds that are ERK inhibitors |
| 摘要 |
Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
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| 申请公布号 |
US2007232610(A1) |
申请公布日期 |
2007.10.04 |
| 申请号 |
US20070705709 |
申请日期 |
2007.02.13 |
| 申请人 |
DENG YONGQI;SHIPPS GERALD W JR;COOPER ALAN;NAN YANG;WANG TONG;SIDDIQUI M A;ZHU HUGH;SUN ROBERT;KELLY JOSEPH M;DOLL RONALD;DESAI JAGDISH;WANG JAMES J;DONG YOUHAO;MADISON VINCENT;XIAO LI;HRUZA ALAN;SHIH NENG-YANG |
发明人 |
DENG YONGQI;SHIPPS GERALD W.JR.;COOPER ALAN;NAN YANG;WANG TONG;SIDDIQUI M. A.;ZHU HUGH;SUN ROBERT;KELLY JOSEPH M.;DOLL RONALD;DESAI JAGDISH;WANG JAMES J.;DONG YOUHAO;MADISON VINCENT;XIAO LI;HRUZA ALAN;SHIH NENG-YANG |
| 分类号 |
A61K31/53;A61K31/401;A61K31/407;A61K31/4439;A61K31/497;A61K31/502;A61K31/506;C07D403/02 |
主分类号 |
A61K31/53 |
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