| 发明名称 |
STEREOSELECTIVE PROCESS AND CRYSTALLINE FORMS OF A CAMPTOTHECIN |
| 摘要 |
A stereoselective process for preparing 7-[(E)-t-butyloxyiminomethyl]-camptothecin (also known as gimatecan) is herein disclosed. With the addition of further dissolution and precipitation steps carried out in appropriate different solvent mixtures, four new crystalline forms of gimatecan are also obtainable by using the same stereoselective process. |
| 申请公布号 |
KR20070097535(A) |
申请公布日期 |
2007.10.04 |
| 申请号 |
KR20077016814 |
申请日期 |
2005.12.16 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
CARMINATI PAOLO;TINTI MARIA ORNELLA;MARZI MAURO;GIORGI FABRIZIO;CABRI WALTER;ALPEGIANI MARCO;VERGANI DOMENICO;GHETTI PAOLO |
| 分类号 |
C07D491/14 |
主分类号 |
C07D491/14 |
| 代理机构 |
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