发明名称 Monte Carlo based model of fluorescence in turbid media and methods and systems for using same to determine intrinsic fluorescence of turbid media
摘要 The subject matter described herein includes a method for modeling fluorescence in turbid media and methods and systems for using the model to determine intrinsic fluorescence of turbid media. According to one aspect, a method for modeling fluorescence of a turbid medium and for using the model to determine intrinsic fluorescence in the turbid medium is provided. The method includes illuminating a turbid medium of interest with an electromagnetic radiation source using a probe of a particular geometry and detecting measured fluorescence for the turbid medium using the probe. At least one set of Monte Carlo simulations is run to determine an escape energy probability map and an absorbed energy density map for the turbid medium. An indication of the intrinsic fluorescence of the turbid medium is determined using the escape probability density map and the absorbed energy density map in a manner that accounts for the geometry of the probe.
申请公布号 US2007232932(A1) 申请公布日期 2007.10.04
申请号 US20070725141 申请日期 2007.03.16
申请人 DUKE UNIVERSITY 发明人 PALMER GREGORY M.;RAMANUJAM NIRMALA
分类号 A61B6/00;G01J3/30 主分类号 A61B6/00
代理机构 代理人
主权项
地址