摘要 |
The invention relates to anti-HCV antibodies and more specifically to neutralizing anti-HCV antibodies and their variable and complementarity determining regions (CDR). In particular, the neutralizing anti-HCV antibodies are neutralizing anti-HCV envelope protein 1 (HCV El) antibodies. Also subject of the invention are compositions comprising these antibodies, CDRs or variable regions, and compounds comprising at least one of the CDRs or variable regions of said antibodies. Further subject of the invention are the application of any of said antibodies, CDRs, variable regions or compounds in HCV prophylaxis, therapy, and diagnosis, as well as methods for producing the antibodies. |
申请人 |
INNOGENETICS N.V.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES;DEPLA, ERIK;PURCELL, ROBERT;BUKH, JENS;EMERSON, SUZANNE, U.;MEUNIER, JEAN-CHRISTOPHE |
发明人 |
DEPLA, ERIK;PURCELL, ROBERT;BUKH, JENS;EMERSON, SUZANNE, U.;MEUNIER, JEAN-CHRISTOPHE |