| 发明名称 |
INTRANASAL PYY FORMULATIONS WITH IMPROVED TRANSMUCOSAL PHARMACOKINETICS |
| 摘要 |
What is described is an aqueous Y2 receptor-binding peptide formulation for enhanced intranasal delivery of a Y2 receptor-binding peptide, comprising said Y2 receptor-binding peptide, a buffer salt, and having a pH between about 3.0 and about 6.0, wherein said buffer salt comprises a net single ionogenic moiety with a pK<SUB>a </SUB>within two pH units of the pH of the formulation.
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| 申请公布号 |
US2007232537(A1) |
申请公布日期 |
2007.10.04 |
| 申请号 |
US20060613109 |
申请日期 |
2006.12.19 |
| 申请人 |
NASTECH PHARMACEUTICAL COMPANY INC. |
发明人 |
COSTANTINO HENRY R.;KLEPPE MARY S.;COHEN ANNEMARIE S.;SILENO ANTHONY P. |
| 分类号 |
A61K38/00;A61K38/03;A61K38/04;A61K38/08;A61K38/10;A61K38/16;C07K4/00;C07K5/00;C07K7/00;C07K9/00;C07K14/00 |
主分类号 |
A61K38/00 |
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