发明名称 |
METHODS TO TRIGGER, MAINTAIN AND MANIPULATE IMMUNE RESPONSES BY TARGETED ADMINISTRATION OF BIOLOGICAL RESPONSE MODIFIERS INTO LYMPHOID ORGANS |
摘要 |
<p>The present invention includes use of a biological response modifier (BRM) to modulate an immune response in a subject while avoiding or limiting common side-effects associate with BRM use. The BRMs of the present invention can be injected into a secondary lymphatic organ of the subject or into an area of relatively high drainage into a secondary lymphatic organ of the subject. The modulated immune response can be general or antigen-specific.</p> |
申请公布号 |
EP1838338(A2) |
申请公布日期 |
2007.10.03 |
申请号 |
EP20050855760 |
申请日期 |
2005.12.29 |
申请人 |
MANNKIND CORPORATION |
发明人 |
KUNDIG, THOMAS;BOT, ADIRAN, ION |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|