发明名称 |
Formulations of anthraquinone derivatives |
摘要 |
A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R'R'' of at least 2 carbon atoms and R' and R'' are each separately selected from C<SUB>1-4 </SUB>alkyl groups and C<SUB>2-4 </SUB>hydroxyalkyl and C<SUB>2-4 </SUB>dihydroxyalkyl groups, or R' and R'' together are a C<SUB>2-6 </SUB>alkylene group, is formulated so that upon dissolution in aqueous solution the pH of the solution is in the range of 5 to 9. The compound may be in the form of salt with a physiologically acceptable acid having a pK<SUB>a </SUB>in the range of -3.0 (minus 3.0) to 9.0
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申请公布号 |
US7276537(B2) |
申请公布日期 |
2007.10.02 |
申请号 |
US20060433545 |
申请日期 |
2006.05.15 |
申请人 |
BTG INTERNATIONAL LIMITED |
发明人 |
DENNY WILLIAM ALEXANDER;PATTERSON LAURENCE HYLTON;HALBERT GAVIN WILLIAM;FORD STEVEN JOHN |
分类号 |
C07C291/04;A61K9/00;A61K31/21;A61K47/02;A61K47/12;A61P35/00;C07C225/34;C07C225/36 |
主分类号 |
C07C291/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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