| 摘要 |
A POLYMORPHIC FORM OF 5-[4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY] BENZYL]THIAZOLIDINE-2,4-DIONE, MALEIC ACID SALT (THE "POLYMORPH") CHARACTERISED IN THAT IT PROVIDES:(i)AN INFRA RED SPECTRUM CONTAINING PEAKS AT 1763, 912, 856 AND 709 CM-1; AND/OR (ii) ARAMAN SPECTRUM CONTAINING PEAKS AT 1762, 1284, 912 AND 888 CM-1; AND/OR(iii)A SOLID-STATE 13C NUCLEAR MAGNETIC RESONANCE SPECTRUM CONTAINING PEAKS AT 111.0, 113.6, 119.8, 129.1,130.9, 131.8, 134.7, 138.7, 146.5, 152.7, 169.5, 171.0, 178.7 PPM;AND/OR(iv)AN X-RAY POWDER DIFFRACTION (XRPD) PATTERN WHICH GIVES CALCULATED LATTICE SPACINGS AT 5.87, 5.30, 4.69, 4.09, 3.88, 3.61, 3.53 AND 3.46 ANGSTROMS;A PROCESS FOR PREPARING SUCH A COMPOUND, A PHARMACEUTICAL COMPOSITION CONTAINING SUCH A COMPOUND AND THE USE OF SUCH A COMPOUND IN MEDICINE.
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