| 发明名称 |
(BIPHENYL) CARBOXYLIC ACIDS AND DERIVATIVES THEREOF. |
| 摘要 |
<p>The present invention relates to compounds having the general formula (I) with the definitions of A, X, R<sub>1</sub>-R<sub>6</sub> given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of ??-secretase activity.</p> |
| 申请公布号 |
MX2007004763(A) |
申请公布日期 |
2007.09.27 |
| 申请号 |
MX20070004763 |
申请日期 |
2005.10.21 |
| 申请人 |
CELLZOME AG |
发明人 |
RICHARD JOHN HARRISON;FRANCIS WILSON;ALISON REID;VALERIE READER;MIHIRO SUNOSE;REMEDIOS HERNANDEZ-PERNI;JEREMY MAJOR;CYRILLE BOUSSARD;SVENJA BURCKHARDT;KATHRYN SMELT;JESS TAYLOR;ADELINE LEFORMAL;ANDREW CANSFIELD |
| 分类号 |
A61K31/192;A61P25/28;C07C59/68;C07C59/72;C07C235/34;C07C311/17;C07C317/22;C07D261/08;C07D295/18;C07D295/22;C07D309/06 |
主分类号 |
A61K31/192 |
| 代理机构 |
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