发明名称 |
SOLID PREPARATION HAVING IMPROVED SOLUBILITY |
摘要 |
<p>Disclosed is a preparation which shows an improved solubility of a poorly water-soluble medicinal agent contained in the preparation even when the medicinal agent is contained in the preparation at a high content. In a preparation comprising a poorly water-soluble medicinal agent and a water-soluble polymer, almost the whole amount of the medicinal agent can be leached out from the preparation by adding nicotinic acid amide and/or urea to the preparation in an amount of 0.1 to 10% by weight, even when the medicinal agent is contained in the preparation at a high content.</p> |
申请公布号 |
WO2007108463(A1) |
申请公布日期 |
2007.09.27 |
申请号 |
WO2007JP55624 |
申请日期 |
2007.03.20 |
申请人 |
SHIONOGI & CO., LTD.;HAYASHI, TAKASHI;TAKAKURA, ASAKO |
发明人 |
HAYASHI, TAKASHI;TAKAKURA, ASAKO |
分类号 |
A61K47/32;A61K9/20;A61K31/4422;A61K47/16;A61K47/22;A61K47/36;A61K47/38;A61K47/42;A61P9/10;A61P9/12 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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