发明名称 SOLID PREPARATION HAVING IMPROVED SOLUBILITY
摘要 <p>Disclosed is a preparation which shows an improved solubility of a poorly water-soluble medicinal agent contained in the preparation even when the medicinal agent is contained in the preparation at a high content. In a preparation comprising a poorly water-soluble medicinal agent and a water-soluble polymer, almost the whole amount of the medicinal agent can be leached out from the preparation by adding nicotinic acid amide and/or urea to the preparation in an amount of 0.1 to 10% by weight, even when the medicinal agent is contained in the preparation at a high content.</p>
申请公布号 WO2007108463(A1) 申请公布日期 2007.09.27
申请号 WO2007JP55624 申请日期 2007.03.20
申请人 SHIONOGI & CO., LTD.;HAYASHI, TAKASHI;TAKAKURA, ASAKO 发明人 HAYASHI, TAKASHI;TAKAKURA, ASAKO
分类号 A61K47/32;A61K9/20;A61K31/4422;A61K47/16;A61K47/22;A61K47/36;A61K47/38;A61K47/42;A61P9/10;A61P9/12 主分类号 A61K47/32
代理机构 代理人
主权项
地址