摘要 |
A compound of the general formula (I) or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof, wherein A represents a variety of six membered nitrogen containing heterocyclic rings, Q is a bond, halogen, C<SUB>1-4 </SUB>alkyl, O, S, SO<SUB>2</SUB>, CO or CS and X<SUB>1</SUB>, X<SUB>2</SUB>, X<SUB>3 </SUB>and X<SUB>4 </SUB>are optionally substituted by 9 specific substituents or one can be nitrogen. Compositions comprising a carrier and at least one compound of formula (I) are also provided. Further provided are methods of treating tyrosine kinase-associated disease states by administering a compound of formula (I) and methods of suppressing the immune system of a subject by administering a compound of formula (I). |
申请人 |
CYTOPIA RESEARCH PTY LTD. |
发明人 |
STYLES, MICHELLE LEANNE;ZENG, JUN;TREUTLEIN, HERBERT RUDOLF;WILKS, ANDREW FREDERICK;KLING, MARCEL ROBERT;BU, XIANYONG;BURNS, CHRISTOPHER JOHN |