发明名称 Tri-peptide hepatitis C serine protease inhibitors
摘要 The present invention relates to compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis c virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis c virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 US7273851(B2) 申请公布日期 2007.09.25
申请号 US20040849107 申请日期 2004.05.19
申请人 ENANTA PHARMACEUTICALS, INC. 发明人 MIAO ZHENWEI;SUN YING;NAKAJIMA SUANNE;TANG DATONG;WANG ZHE;OR YAT S.
分类号 A61K38/00;A61K38/05;C07K5/06;C07K5/083 主分类号 A61K38/00
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