发明名称 |
Process for producing a solid dispersion of an active ingredient |
摘要 |
A process for producing a solid dispersion of an active ingredient which comprises feeding the active ingredient and a matrix-forming agent to an extruder and forming a uniform extrudate, wherein the extruder comprises at least two rotating shafts (2), each of the shafts (2) carrying a plurality of processing elements disposed axially one behind the other, the processing elements defining (i) a feeding and conveying section (A), (ii) at least one mixing section (B), and (iii) a discharging section (E), wherein the processing element(s) defining the mixing section (B) comprise(s) a mixing element (11, 12, 13) that is derived from a screw type element (figure 2). |
申请公布号 |
EP1832281(A1) |
申请公布日期 |
2007.09.12 |
申请号 |
EP20060004999 |
申请日期 |
2006.03.10 |
申请人 |
ABBOTT GMBH & CO. KG |
发明人 |
KESSLER, THOMAS;BREITENBACH, JOERG;SCHMIDT, CHRISTOPH;DEGENHARDT, MATTHIAS;ROSENBERG, JOERG;KRULL, HARALD |
分类号 |
A61K9/20;B29C31/00;B29C35/02;B29C47/00;B29C47/10;B29C47/38;B29C47/40;B29C47/60;B29C47/64;B29C47/76;B29C47/82 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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