The invention provides novel inhibitors of hedgehog signaling that are usefulas a therapeutic agents for treating malignancies where the compounds have thegeneral formula I: wherein A, X, Y, R1, R2, R3,R4, and n are as described herein.
申请公布号
MX2007002584(A)
申请公布日期
2007.09.07
申请号
MX20070002584
申请日期
2005.09.02
申请人
GENENTECH, INC.
发明人
DANIEL P. SUTHERLIN;JANET GUNZNER;MARK STANLEY;LIANG BAO;GEORGETTE CASTANEDO;REBECCA LALONDE;SHUMEI WANG;MARK REYNOLDS;SCOTT SAVAGE;KIMBERLY MALESKY;MICHAEL DINA