发明名称 ANTIBODIES AGAINST IL-13 RECEPTOR ALPHA1 AND USES THEREOF
摘要 An antibody binding to IL-13REl, inhibiting IL-13 bioactivity and comprising a variable heavy and a variable light chain, characterized in that the variable heavy chain amino acid sequence CDR3 of said antibody is selected from the group consisting of the heavy chain CDR3 sequences of SEQ ID NO: 1, 3, 5, 7 or 9 is useful in the treatment of asthma and allergic diseases.
申请公布号 KR20070091180(A) 申请公布日期 2007.09.07
申请号 KR20077015296 申请日期 2006.01.02
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ENDL JOSEF;FUENTES MARIA;GRAUS YVO;GROSSMANN ADELBERT;NEUMANN SEBASTIAN;PARREN PAUL;REBERS FRANK;REGULA JOERG;SCHUMACHER RALF;SEEBER STEFAN;STRACKE JAN;STUBENRAUCH KAY GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE;VEREECKEN VERPLOEGEN SANDRA
分类号 C07K16/00;C12N5/06;C12P21/06 主分类号 C07K16/00
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