| 摘要 |
PROBLEM TO BE SOLVED: To provide a new method for industrially producing 4-chloropyridine-2-carboxylic chloride, by which the 4-chloropyridine-2-carboxylic chloride can be obtained in a high yield. SOLUTION: This method for producing the 4-chloropyridine-2-carboxylic chloride is characterized by reacting pyridine-2-carboxylic acid or pyridine-2-carboxylic acid hydrogen halide with thionyl chloride in the presence of a bromide as a catalyst and an N-substituted formamide represented by the general formula (4) (R<SB>1</SB>and R<SB>2</SB>are each independently a group selected from the group consisting of an alkyl or an aryl, provided that R<SB>1</SB>and R<SB>2</SB>may be bound to each other to form a cyclic amino group) as a catalyst. COPYRIGHT: (C)2007,JPO&INPIT
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