| 发明名称 |
TREATMENT OF alpha;-GALACTOSIDASE A DEFICIENCY |
| 摘要 |
The invention provides highly purified alpha-Gal A, and various methods for purifying it; alpha-Gal A preparations with altered charge and methods for making those preparations; alpha-Gal A preparations that have an extended circulating half-life in a mammalian host, and methods for making same; and methods and dosages for administering an alpha-Gal A preparation to a subject. |
| 申请公布号 |
KR20070090277(A) |
申请公布日期 |
2007.09.05 |
| 申请号 |
KR20077019031 |
申请日期 |
2000.03.09 |
| 申请人 |
TRANSKARYOTIC THERAPIES, INC. |
发明人 |
SELDEN RICHARD F.;BOROWSKI MARIANNE;KINOSHITA CAROL M.;TRECO DOUGLAS A.;WILLIAMS MELANIE D.;SCHUETZ THOMAS J.;DANIEL PETER F. |
| 分类号 |
A61K38/12;A61K38/47;A61K38/00;A61K48/00;C07K14/435;C07K14/61;C12N9/24;C12N9/40;C12N15/54;C12N15/56 |
主分类号 |
A61K38/12 |
| 代理机构 |
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