| 摘要 |
Derivatives of camptothecin are disclosed and are represented by general formula (I):
wherein when R 2 is H, R 1 is a C 2 -C 4 alkyl group, a C 6 -C 15 alkyl group, a C 3 -C 8 cycloalkyl group, a C 2 -C 15 alkenyl group or a C 2 -C 15 epoxy group; and when R 2 is a nitro group, R 1 is a C 1 -C 15 alkyl group, a C 2 -C 15 alkenyl group, a C 3 -C 8 cycloalkyl group, or an epoxy group. Processes for making these derivatives and for using them in cancer treatment are also disclosed.
|
