Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof

摘要

Provided herein are compounds of the formula (I): wherein R¹-R⁸ are as described herein, R⁴ being phthalazinyl, pyrazinyl, pyridazinyl, or quinoxalinyl. Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine, or dopamine.