| 发明名称 |
COMPOUND AND METHOD OF PREPARATION THEREOF |
| 摘要 |
FIELD: complexing compounds. ^ SUBSTANCE: invention provides macrocyclic metal complexes, preparation thereof, and application thereof to form conjugates with biomolecules. Such conjugates are appropriate for use as contrast substances in NMR diagnostics and for use in radiotherapy. ^ EFFECT: enhanced relaxation ability and possibility to control it due to special ligands attached to macrocycles. ^ 12 cl, 2 tbl, 91 ex |
| 申请公布号 |
RU2305096(C2) |
申请公布日期 |
2007.08.27 |
| 申请号 |
RU20040105261 |
申请日期 |
2002.07.18 |
| 申请人 |
SHERING AG |
发明人 |
PLATTSEK IOGANNES;SHMITT-VILLIKH KHERIBERT;MIKHL' GJUNTER;FRENTSEL' TOMAS;ZJUL'TSLE DETLEF;BAUER KHANS;RADJUKHEL' BERND;VAJNMANN KHANNS-JOAKHIM;SHIRMER KHEJKO |
| 分类号 |
C07D257/12;C07D403/04;A61K47/48;A61K49/00;A61K49/08;A61K49/14;A61K51/00;C07D257/02;C07F5/00;C07F9/38 |
主分类号 |
C07D257/12 |
| 代理机构 |
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| 地址 |
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