发明名称 |
METHOD FOR THE PREPARATION OF ENANTIOMER FORMS OF CIS-CONFIGURED 3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES USING HYDROLASES |
摘要 |
The present invention relates to a process for preparing chiral non-racemic cis-configured cyclohexanols or cyclohexanol derivatives of the formula (I) Cis-configured hydroxyl-cyclohexane carboxylic acid derivatives of formula (I) are central building blocks or immediate precursors for the medicinally active compounds which allow a therapeutic modulation of the lipid and/or carbohydrate metabolism and are thus suitable for preventing and/or treating type II diabetes, hyperglycemia and artherosclerosis. The cis-configured hydroxyl-cyclohexane carboxylic acid derivatives of formula (I) are central building blocks or immediate precursors for the medicinally active compounds described in the prior art.
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申请公布号 |
US2007197788(A1) |
申请公布日期 |
2007.08.23 |
申请号 |
US20070669545 |
申请日期 |
2007.01.31 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
HOLLA WOLFGANG;KEIL STEFANIE;TAPPERTZHOFEN CHRISTOPH |
分类号 |
C07F7/02;C07D263/02;C07D413/02 |
主分类号 |
C07F7/02 |
代理机构 |
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地址 |
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