发明名称 Advanced route for the synthesis of cPLA2 inhibitors
摘要 A process for making a compound of formula (I) in which process the compound HC≡C-(CH<SUB>2</SUB>)<SUB>n</SUB>-NH<SUB>2 </SUB>is reacted with the compound R<SUB>1</SUB>-SO<SUB>2</SUB>Cl to produce an intermediate compound, which intermediate compound is then reacted with the compound of formula to produce the compound of formula (I), and compounds produced by the process of this invention. The terms R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4 </SUB>and n have the definitions set forth in the specification.
申请公布号 US7259277(B2) 申请公布日期 2007.08.21
申请号 US20050076117 申请日期 2005.03.08
申请人 WYETH 发明人 WU YANZHONG;RAVEENDRATH PANOLIL
分类号 C07C311/03;C07C255/58;C07C303/38;C07C303/40;C07C311/05;C07C311/13;C07D209/14 主分类号 C07C311/03
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