NEW N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES WITH ANALGESIC PROPERTIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

The present invention relates to a series of new N-acylated 4-hydroxyphenylamine derivatives, linked via an alkylene bridge to the nitrogen atom of a l,2-benzisothiazol-3(2H)-one 1,1-dioxide group, of formula (I), in which n is a number from I to 5, and to processes for preparing these derivatives and to pharmaceutical compositions containing said derivatives; these compounds possess high analgesic activity free from antipyretic activity, and they display little hepatotoxic effect.