发明名称 |
MODULATION OF WRN-MEDIATED TELOMERE-INITIATED CELL SIGNALING. |
摘要 |
<p>The use of modulators of WRN is described. Activators of WRN may be used to induce growth arrest, apoptosis or proliferative senescence, whereas inhibitors of WRN may be used to reduce growth arrest, apoptosis or prolifertative senescence. Methods of identifying modulators of WRN are also described.</p> |
申请公布号 |
MXPA06013263(A) |
申请公布日期 |
2007.08.14 |
申请号 |
MX2006PA13263 |
申请日期 |
2005.05.19 |
申请人 |
TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
BARBARA A. GILCHREST;MARK S. ELLER |
分类号 |
C12N9/14;C12N15/113;G01N33/50;G01N33/68 |
主分类号 |
C12N9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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