发明名称 |
Enhancing the efficacy of immunotherapies by supplementing with complement |
摘要 |
The present invention is directed to a composition and method for enhancing the complement-mediated cytotoxicity of therapeutic antibodies for their target cells (i.e. those cells displaying the target epitope). More particularly the present invention enhances the efficacy of such therapies by providing a supplemental source of complement.
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申请公布号 |
US7255858(B2) |
申请公布日期 |
2007.08.14 |
申请号 |
US20040486438 |
申请日期 |
2004.02.09 |
申请人 |
UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
TAYLOR RONALD P.;LINDORFER MARGARET A.;SOLGA MICHAEL D.;KENNEDY ADAM |
分类号 |
A61K39/395;A61K38/54;A61K39/00;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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