The instant invention provides for compounds which comprise substituted 3-aryl-4-hydroxyquinolin-2(1H)-ones that inhibit FAS activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting FAS activity by administering the compound to a patient in need of treatment of cancer.
申请公布号
WO2007089634(A2)
申请公布日期
2007.08.09
申请号
WO2007US02254
申请日期
2007.01.26
申请人
MERCK & CO., INC.;GOULET, MARK, T.;MUNOZ, BENITO;RIVKIN, ALEXEY, A.