发明名称 |
NOVEL PHOSPHOLIPASE D |
摘要 |
A modified phospholipase D having an ability to synthesize phosphatidylinositol which contains: (A) an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO:2 by substitution of at least one of the amino acid residues at the 187-, 191- and 385-positions by other amino acid residue(s); or (B) an amino acid sequence of a polypeptide derived from the amino acid sequence as described in the above (A) by substitution, deletion, insertion and/or addition of at least one amino acid residue at a position different from the 187-, 191- and 385-positions and having an ability to synthesize phosphatidylinositol. By using this modified phospholipase D, phosphatidylinositol can be efficiently produced from a phospholipid. It is also intended to provide a method of screening a phospholipase D having an ability to synthesize an acylglycerophospholipid having glycol group. |
申请公布号 |
WO2007089038(A1) |
申请公布日期 |
2007.08.09 |
申请号 |
WO2007JP52172 |
申请日期 |
2007.02.01 |
申请人 |
NAGOYA UNIVERSITY;IWASAKI, YUGO;NAKANO, HIDEO;TAKAHASHI, TETSUYA |
发明人 |
IWASAKI, YUGO;NAKANO, HIDEO;TAKAHASHI, TETSUYA |
分类号 |
C12N15/00;C12N9/16;C12N15/09;C12P9/00;C12Q1/34 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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