发明名称 |
Large-Scale Production of Human Serum Butyrylcholinesterase as a Bioscavenger |
摘要 |
Disclosed herein are methods for the large-scale preparation of human butyrylcholinesterase (HuBChE) preparations from Cohn Fraction IV-4. As disclosed, the methods provide HuBChE preparations that are about 99% or more pure with recovery yields of about 60%. Also disclosed are the pharmacokinetics, safety and toxicity, stability and efficacy of the HuBChE preparations.
|
申请公布号 |
US2007184045(A1) |
申请公布日期 |
2007.08.09 |
申请号 |
US20070733246 |
申请日期 |
2007.04.10 |
申请人 |
DOCTOR BHUPENDRA P;SAXENA ASHIMA;SUN WEI;LUO CHUNYUAN;TIPPARAJU PRASANTHI;KOPLOVITZ IRWIN;LENZ DAVID E;ROSS MICHELLE C |
发明人 |
DOCTOR BHUPENDRA P.;SAXENA ASHIMA;SUN WEI;LUO CHUNYUAN;TIPPARAJU PRASANTHI;KOPLOVITZ IRWIN;LENZ DAVID E.;ROSS MICHELLE C. |
分类号 |
A61K38/46;C12N9/18 |
主分类号 |
A61K38/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|