Verfahren zur Herstellung eines Human-Papillomavirusvakzins mit Disassemblierten und Reassembliertenn Virusaehnlichen Partikeln

摘要

Human Papillomavirus vaccine formulations which contain virus-like particles (VLPs) can be made more stable and have an enhanced shelf-life, by treating the VLPs to a disassembly and reassembly process. Also provided are formulation buffers to long term stable storage of VLPs.