发明名称 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PERSISTENT INFECTIONS AND CANCER BY INHIBITING THE PROGRAMMED CELL DEATH 1 (PD-1) PATHWAY
摘要 The present invention provides methods and compositions for the treatment, prevention, or reduction of persistent infections, such as chronic infections, latent infections, and slow infections and cancer. The methods and compositions of the invention are also useful for the alleviation of one or more symptoms associated with such infections and cancer.
申请公布号 WO2006133396(A3) 申请公布日期 2007.08.09
申请号 WO2006US22423 申请日期 2006.06.08
申请人 DANA-FARBER CANCER INSTITUTE;THE BRIGHAM AND WOMEN'S HOSPITAL, INC.;EMORY UNIVERSITY;FREEMAN, GORDAN;SHARPE, ARLENE;DORFMAN, DAVID, M.;AHMED, RAFI;BARBER, DANIEL;WHERRY, E., JOHN 发明人 FREEMAN, GORDAN;SHARPE, ARLENE;DORFMAN, DAVID, M.;AHMED, RAFI;BARBER, DANIEL;WHERRY, E., JOHN
分类号 A61K39/395;C07K16/28;G01N33/53 主分类号 A61K39/395
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