发明名称 |
NON-STEROIDAL ANTI-INFLAMMATORY DRUG ACTIVATED GENE WITH ANTI-TUMORIGENIC PROPERTIES |
摘要 |
The present invention provides methods and compositions for drug screens to identify and characterize agents that are agonistic or antagonistic to activation of the promoter region of the NAG-1 gone. Activation of the NAG-1 gene is associated with the apoptotic elimination of cancer cells both in vitro and in vivo. The invention also provides novel promoter region sequences of the NAG-1 gene.
|
申请公布号 |
US2007180543(A1) |
申请公布日期 |
2007.08.02 |
申请号 |
US20060563586 |
申请日期 |
2006.11.27 |
申请人 |
GOVERNMENT OF THE U.S.A, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH & HUMAN SERVICES |
发明人 |
ELING THOMAS E.;BAEK SEUNG J. |
分类号 |
A01K67/027;A61K39/395;A61K48/00;A61P35/00;C07H21/04;C07K14/47;C07K14/495;C12N15/12;G01N33/50 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|