ENGINEERED ANTIBODIES WITH NEW WORLD PRIMATE FRAMEWORK REGIONS
摘要
The present invention provides an antibody or antigen-binding portion thereof having a variable region comprising at least two complementarity determining regions (CDRs) and at least three framework regions. The the framework regions are, or are derived from New World primate framework regions, and at least one of the CDRs is a non-New World primate CDR.
申请公布号
WO2007019620(A8)
申请公布日期
2007.08.02
申请号
WO2006AU01165
申请日期
2006.08.15
申请人
PEPTECH LIMITED;JENNINGS, PHILIP, ANTHONY;DOYLE, ANTHONY, GERARD;CLARKE, ADAM, WILLIAM;GAY, ROBERT, DANIEL
发明人
JENNINGS, PHILIP, ANTHONY;DOYLE, ANTHONY, GERARD;CLARKE, ADAM, WILLIAM;GAY, ROBERT, DANIEL