发明名称 |
Antagonist peptides to VEGF receptor Flt-1 |
摘要 |
The present invention provides a polypeptide or a pharmacologically acceptable salt thereof comprising one or more, identical or different, amino acid sequences of A-W-H-X1-D-X2-X3-X4-W-W-X5-X6-X7-X8-B (the meaning of each symbol in the formula is defined in the description) and a pharmaceutical composition for treating an angiogenic disease such as a solid tumor comprising said polypeptide. The present invention also relates to a polynucleotide encoding the above-mentioned polypeptide and use of the polynucleotide in gene therapy.
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申请公布号 |
US7250395(B2) |
申请公布日期 |
2007.07.31 |
申请号 |
US20040489344 |
申请日期 |
2004.10.28 |
申请人 |
BEIJING INSTITUTE FOR CANCER RESEARCH |
发明人 |
SHOU CHENGCHAO;LEI HETIAN;AN PING;WU JIAN;MENG LIN;LIU XIAOYING |
分类号 |
A61K38/10;A61K38/16;A61K48/00;A61P35/00;C07K14/71;C12N15/32 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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