ESTERS OF (+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL AND THEIR USE AS PRODRUGS OF THE 5HT2A RECEPTOR ANTAGONIST MDL 110,907

摘要

The compounds antagonize the effects of serotonin at the 5HT2A receptor and are used for the treatment of various conditions, such as for example, psychoses such as schizophrenia. They have the formula wherein R is C4-C20 alkyl. The invention also relates to their pharmaceutical forms, to methods for their preparation and application.