| 发明名称 |
GLYCOPEPTIDE OF GLYCIRRISINE ACID WITH L-PROLIN HUMORAL IMMUNE RESPONSE STIMULATING |
| 摘要 |
FIELD: biochemistry. ^ SUBSTANCE: describes is new chemical compound, namely glycirrisine acid derivative with L-prolin: 3-O-{2-O-[N-(beta-O-glucopyranosyluronoyl)-L-prolin-N-(beta-D-glucopyranosyluronoyl)-L-prolin]}-(3beta,20beta)-11-oxoolean-12-en-30-oic acid, stimulating of humoral immune response. Said compound has low toxicity and increases agglutinins levels (by 3,7 times) and hemolysines level (by 3 times) in mouth blood in contrast with control while administrating of 2 mg/kg. ^ EFFECT: preparation with increased stimulating activity in relation to agglutinin production. ^ 1 cl, 2 ex |
| 申请公布号 |
RU2303601(C2) |
申请公布日期 |
2007.07.27 |
| 申请号 |
RU20050104203 |
申请日期 |
2005.02.16 |
| 申请人 |
INSTITUT ORGANICHESKOJ KHIMII UFIMSKOGO NAUCHNOGOTSENTRA RAN;GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "BASHKIRSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET FEDERAL'NOGO AGENTSTVA PO ZDRAVOOKHRANENIJU I SOTSIAL'NOMU RAZVITIJU" (GOU VPO BGMU ROSZDRAVA) |
发明人 |
KONDRATENKO RIMMA MINIBAEVNA;BALTINA LIJA ALEKSANDROVNA;BASCHENKO NATAL'JA ZHANOVNA;BALTINA LIDIJA ASHRAFOVNA;ISMAGILOVA ASIJA FAKHRETDINOVNA;KHALIULLIN FERKAT ADEL'ZJANOVICH;GALIN FANUR ZUFAROVICH;TOLSTIKOV GENRIKH ALEKSANDROVICH |
| 分类号 |
C07J53/00;A61P37/04;C07J63/00 |
主分类号 |
C07J53/00 |
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