| 发明名称 |
Xanthones, thioxanthones and acridinones as dna-pk inhibitors |
| 摘要 |
Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating cancer treatment are disclosed.
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| 申请公布号 |
US2007167441(A1) |
申请公布日期 |
2007.07.19 |
| 申请号 |
US20040550978 |
申请日期 |
2004.03.19 |
| 申请人 |
HALBROOK JAMES W;KESICKI EDWARD A;BURGESS LAURENCE E;SCHLACHTER STEPHEN T;EARY CHARLES T;SCHIRO JUSTIN G |
发明人 |
HALBROOK JAMES W.;KESICKI EDWARD A.;BURGESS LAURENCE E.;SCHLACHTER STEPHEN T.;EARY CHARLES T.;SCHIRO JUSTIN G. |
| 分类号 |
A61K31/541;A61K31/382;A61K31/4436;A61K31/453;A61K31/496;A61K31/5377;A61K45/06;A61P35/00;C07D219/06;C07D219/16;C07D311/86;C07D401/06;C07D405/04;C07D405/12;C07D409/02;C07D413/02;C07D417/02;C07D471/04;C07F9/6558;C07F9/6561 |
主分类号 |
A61K31/541 |
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