发明名称 |
Albumin-purification method comprising a nanofiltration step, solution, and composition for therapeutic use containing the same |
摘要 |
The invention relates to an albumin-purification method comprising a step consisting in subjecting an aqueous albumin solution, with a concentration of between 15 g/l and 80 g/l and a pH of not less than 7, to nanofiltration in a temperature range of between 15 DEG C. and 55 DEG C. The invention also relates to: a virally-safe aqueous albumin solution which can be obtained using the invention method and in which the sites for the transport and binding of the active therapeutic ingredients of the albumin are available; and an albumin composition for therapeutic use, which is obtained by adapting the albumin solution that is intended for clinical use. |
申请公布号 |
US2007161122(A1) |
申请公布日期 |
2007.07.12 |
申请号 |
US20050589825 |
申请日期 |
2005.02.23 |
申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
BOULANGE PAUL;CHTOUROU SAMI;BOYER STEPHANE;SCHMITTHAEUSLER ROLAND;PADRAZZI BRUNO |
分类号 |
G01N33/543;A61K38/00;C07K14/76;C07K14/765 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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