| 发明名称 |
Method of treating neurodegenerative disease |
| 摘要 |
Aspects featured in the invention relate to compositions and methods for inhibiting alpha-synuclein (SNCA) gene expression, such as for the treatment of neurodegenerative disorders. An anti-SNCA agent featured herein that targets the SNCA gene can have been modified to alter distribution in favor of neural cells.
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| 申请公布号 |
US2007161595(A1) |
申请公布日期 |
2007.07.12 |
| 申请号 |
US20060548890 |
申请日期 |
2006.10.12 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
BUMCROT DAVID;FARRER MATTHEW J.;MARAGANORE DEMETRIUS M.;VORNLOCHER HANS-PETER |
| 分类号 |
A61K48/00;C07H21/02;C12Q1/68 |
主分类号 |
A61K48/00 |
| 代理机构 |
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